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Recombinant Mouse Thioredoxin-interacting Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9833
Species: Mouse
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 397

Product NumberDescriptionPrice
QP9833-ye-10ug Size: 10 ug, Tag: His $ 88.00
QP9833-ye-50ug Size: 50 ug, Tag: His $ 218.00
QP9833-ye-100ug Size: 100 ug, Tag: His $ 348.00
QP9833-ye-200ug Size: 200 ug, Tag: His $ 568.00
QP9833-ye-500ug Size: 500 ug, Tag: His $ 988.00
QP9833-ye-1mg Size: 1 mg, Tag: His $ 1,618.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9833-ye-10ug
Recombinant Mouse Thioredoxin-interacting protein Protein General Information
Alternate Names
VDUP1; THIF; AA682105; 1200008J08Rik; Hyplip1; Tbp-2
Curated Database and Bioinformatic Data
Gene SymbolTxnip
Entrez Gene ID56338
Ensemble Gene IDENSMUSG00000038393
RefSeq Protein Accession(s)NP_001009935.1
RefSeq mRNA Accession(s)NM_001009935.2, NM_023719.2
UniProt ID(s)Q8BG60
UniGene ID(s)Mm.410189
COSMIC ID Link(s)Txnip
KEGG Gene ID(s)mmu:56338
General Description of Recombinant Mouse Thioredoxin-interacting protein Protein.
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) . Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.

Mouse Thioredoxin-interacting protein Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Thioredoxin-interacting protein based upon sequence from Mouse
Host: QP9833 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Thioredoxin-interacting protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9833.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Gln397
Amino Acid Sequence: MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS QQCKQTLDYL RYEDTLLLEE QPTAGENEMV IMRPGNKYEY KFGFELPQGP LGTSFKGKYG CVDYWVKAFL DRPSQPTQEA KKNFEVMDLV DVNTPDLMAP VSAKKEKKVS CMFIPDGRVS VSARIDRKGF CEGDDISIHA DFENTCSRIV VPKAAIVARH TYLANGQTKV FTQKLSSVRG NHIISGTCAS WRGKSLRVQK IRPSILGCNI LKVEYSLLIY VSVPGSKKVI LDLPLVIGSR SGLSSRTSSM ASRTSSEMSW IDLNIPDTPE APPCYMDIIP EDHRLESPTT PLLDDVDDSQ DSPIFMYAPE FQFMPPPTYT EVDPCVLNNN NNNNNVQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Thioredoxin-interacting protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse Thioredoxin-interacting Protein