SDS-PAGE separation of QP9861 followed by commassie total protein stain results in a primary band consistent with reported data for Twinkle protein
SDS-PAGE separation of QP9861 followed by commassie total protein stain results in a primary band consistent with reported data for Twinkle protein

Recombinant Human Twinkle protein, mitochondrial Protein

$ 468.00$ 1,298.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9861
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 653

Product NumberDescriptionPrice
QP9861-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9861-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9861-ye-10ug
Recombinant Human Twinkle protein, mitochondrial Protein General Information
Alternate Names
MTDPS7; PEO; PEOA3; TWINL; C10orf2; PRLTS5; SCA8; ATXN8; IOSCA; PEO1; SANDO
Curated Database and Bioinformatic Data
Gene SymbolPEO1
Entrez Gene ID56652
Ensemble Gene IDENSG00000107815
RefSeq Protein Accession(s)NP_001157284.1
RefSeq mRNA Accession(s)NM_001163812.1, NM_021830.4
UniProt ID(s)Q96RR1
UniGene ID(s)Hs.22678
HGNC ID(s)HGNC:1160
KEGG Gene ID(s)hsa:56652
PharmGKB ID(s)PA162377675
General Description of Recombinant Human Twinkle protein, mitochondrial Protein.
Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as tplate to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.

Human Twinkle protein, mitochondrial Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Twinkle protein, mitochondrial based upon sequence from Human
Host: QP9861 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Twinkle protein, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9861.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala32 - Lys684
Amino Acid Sequence: APGPPRRRYR KETLQALDMP VLPVTATEIR QYLRGHGIPF QDGHSCLRAL SPFAESSQLK GQTGVTTSFS LFIDKTTGHF LCMTSLAEGS WEDFQASVEG RGDGAREGFL LSKAPEFEDS EEVRRIWNRA IPLWELPDQE EVQLADTMFG LTKVTDDTLK RFSVRYLRPA RSLVFPWFSP GGSGLRGLKL LEAKCQGDGV SYEETTIPRP SAYHNLFGLP LISRRDAEVV LTSRELDSLA LNQSTGLPTL TLPRGTTCLP PALLPYLEQF RRIVFWLGDD LRSWEAAKLF ARKLNPKRCF LVRPGDQQPR PLEALNGGFN LSRILRTALP AWHKSIVSFR QLREEVLGEL SNVEQAAGLR WSRFPDLNRI LKGHRKGELT VFTGPTGSGK TTFISEYALD LCSQGVNTLW GSFEISNVRL ARVMLTQFAE GRLEDQLDKY DHWADRFEDL PLYFMTFHGQ QSIRTVIDTM QHAVYVYDIC HVIIDNLQFM MGHEQLSTDR IAAQDYIIGV FRKFATDNNC HVTLVIHPRK EDDDKELQTA SIFGSAKASQ EADNVLILQD RKLVTGPGKR YLQVSKNRFD GDVGVFPLEF NKNSLTFSIP PKNKARLKKI KDDTGPVAKK PSSGKKGATT QNSEICSGQA PTPDQPDTSK RSK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Twinkle protein, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Twinkle protein, mitochondrial Protein

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