SDS-PAGE separation of QP9886 followed by commassie total protein stain results in a primary band consistent with reported data for Mixed lineage kinase domain-like protein. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP9886 followed by commassie total protein stain results in a primary band consistent with reported data for Mixed lineage kinase domain-like protein. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Mouse Mixed lineage kinase domain-like Protein

$ 648.00$ 1,778.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9886
Species: Mouse
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 472

Product NumberDescriptionPrice
QP9886-ye-100ug Size: 100 ug, Tag: His $ 578.00
QP9886-ye-500ug Size: 500 ug, Tag: His $ 1,588.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9886-ye-10ug
Recombinant Mouse Mixed lineage kinase domain-like protein Protein General Information
Alternate Names
9130019I15Rik
Curated Database and Bioinformatic Data
Gene SymbolMLKL
Entrez Gene ID74568
Ensemble Gene IDENSMUSG00000012519
RefSeq Protein Accession(s)NP_001297542.1
RefSeq mRNA Accession(s)NM_001310613.1, NM_029005.3, XM_006531442.2
UniProt ID(s)Q9D2Y4
UniGene ID(s)Mm.207971
COSMIC ID Link(s)MLKL
KEGG Gene ID(s)mmu:74568
General Description of Recombinant Mouse Mixed lineage kinase domain-like protein Protein.
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma mbrane and execution of programmed necrosis characterized by calcium influx and plasma mbrane damage. Does not have protein kinase activity.

Mouse Mixed lineage kinase domain-like protein Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Mixed lineage kinase domain-like protein based upon sequence from Mouse
Host: QP9886 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Mixed lineage kinase domain-like protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9886.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Val472
Amino Acid Sequence: MDKLGQIIKL GQLIYEQCEK MKYCRKQCQR LGNRVHGLLQ PLQRLQAQGK KNLPDDITAA LGRFDEVLKE ANQQIEKFSK KSHIWKFVSV GNDKILFHEV NEKLRDVWEE LLLLLQVYHW NTVSDVSQPA SWQQEDRQDA EEDGNENMKV ILMQLQISVE EINKTLKQCS LKPTQEIPQD LQIKEIPKEH LGPPWTKLKT SKMSTIYRGE YHRSPVTIKV FNNPQAESVG IVRFTFNDEI KTMKKFDSPN ILRIFGICID QTVKPPEFSI VMEYCELGTL RELLDREKDL TMSVRSLLVL RAARGLYRLH HSETLHRNIS SSSFLVAGGY QVKLAGFELS KTQNSISRTA KSTKAERSSS TIYVSPERLK NPFCLYDIKA EIYSFGIVLW EIATGKIPFE GCDSKKIREL VAEDKKQEPV GQDCPELLRE IINECRAHEP SQRPSVDGRS LSGRERILER LSAVEESTDK KV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Mixed lineage kinase domain-like protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse Mixed lineage kinase domain-like Protein

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