SDS-PAGE separation of QP9935 followed by commassie total protein stain results in a primary band consistent with reported data for F-box only protein 3. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP9935 followed by commassie total protein stain results in a primary band consistent with reported data for F-box only protein 3. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human F-box only protein 1

$ 468.00$ 2,008.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9935
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 471

Product NumberDescriptionPrice
QP9935-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9935-ye-1mg Size: 1 mg, Tag: His $ 2,008.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9935-ye-10ug
Recombinant Human F-box only protein 3 Protein General Information
Alternate Names
FBA; FBX3
Curated Database and Bioinformatic Data
Gene SymbolFBXO3
Entrez Gene ID26273
Ensemble Gene IDENSG00000110429
RefSeq Protein Accession(s)NP_036307.2
RefSeq mRNA Accession(s)NM_012175.3, NM_033406.2
UniProt ID(s)Q9UK99
UniGene ID(s)Hs.406787
HGNC ID(s)HGNC:13582
COSMIC ID Link(s)FBXO3
KEGG Gene ID(s)hsa:26273
PharmGKB ID(s)PA28040
General Description of Recombinant Human F-box only protein 3 Protein.
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Human F-box only protein 3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant F-box only protein 3 based upon sequence from Human
Host: QP9935 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) F-box only protein 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9935.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Phe471
Amino Acid Sequence: MAAMETETAP LTLESLPTDP LLLILSFLDY RDLINCCYVS RRLSQLSSHD PLWRRHCKKY WLISEEEKTQ KNQCWKSLFI DTYSDVGRYI DHYAAIKKAW DDLKKYLEPR CPRMVLSLKE GAREEDLDAV EAQIGCKLPD DYRCSYRIHN GQKLVVPGLL GSMALSNHYR SEDLLDVDTA AGGFQQRQGL KYCLPLTFCI HTGLSQYIAV EAAEGRNKNE VFYQCPDQMA RNPAAIDMFI IGATFTDWFT SYVKNVVSGG FPIIRDQIFR YVHDPECVAT TGDITVSVST SFLPELSSVH PPHYFFTYRI RIEMSKDALP EKACQLDSRY WRITNAKGDV EEVQGPGVVG EFPIISPGRV YEYTSCTTFS TTSGYMEGYY TFHFLYFKDK IFNVAIPRFH MACPTFRVSI ARLEMGPDEY EEMEEEEEEE EEEDEDDDSA DMDESDEDDE EERRRRVFDV PIRRRRCSRL F
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human F-box only protein 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human F-box only protein 1

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