SDS-PAGE separation of QP9939 followed by commassie total protein stain results in a primary band consistent with reported data for Podocalyxin. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat Podocalyxin Protein

$ 578.00 – $ 1,588.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP9939
Species: Rat
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 362

Product Number	Description	Price
QP9939-ye-100ug	Size: 100 ug, Tag: His	$ 648.00
QP9939-ye-500ug	Size: 500 ug, Tag: His	$ 1,778.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP9939-ye-10ug

Recombinant Rat Podocalyxin Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	PODXL
Entrez Gene ID	192181
Ensemble Gene ID	ENSRNOG00000012495
RefSeq Protein Accession(s)	NP_620203.1
RefSeq mRNA Accession(s)	NM_138848.1, XM_008762758.2, XM_017592427.1
UniProt ID(s)	Q9WTQ2
UniGene ID(s)	Rn.162741
COSMIC ID Link(s)	PODXL
KEGG Gene ID(s)	rno:192181
General Description of Recombinant Rat Podocalyxin Protein.
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma mbrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Rat Podocalyxin Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Podocalyxin based upon sequence from Rat

Host: QP9939 protein expressed in Yeast.

Tag: His

Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) Podocalyxin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP9939.

Bioactivity Data: Untested

Full Length? Extracellular Domain

Expression Region: Gln25 - Ser386

Amino Acid Sequence: QDNGNKTDTS DITSIDQNQD KPATNQPSNA TPKSSVQPPT PTSISTSSPD PKATQSSNSS VTTTSDSTTD RTSSSTSTVP TTSNSGQTVS SGGKSSDKIT TALPTTLGPV NASSQPTDLN TSTKLPSTPT TNSTASPHQP VSHSEGQHTT VQSSSASVSS SDNTTLLWIL TTSKPTGTSE GTQPIAISTP GITTPVSTPL QPTGSPGGTE SVPTTEEFTH STSSWTPVVS QGPSTPSSTW TSGSYKLKCD PAIKPHEELL ILNLTRDSFC KGSPPNERFL ELLCHSAKAS FKPAEDSCAL ELAPILDNMS -QAVAVKRIV IETKLSPKAV FELLKDKWDD LTEAGVIDIH LGKEGPPEVN EDRFS

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Rat Podocalyxin Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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