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Recombinant Human 5-hydroxytryptamine receptor 1B Protein

$ 1,648.00$ 4,858.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9954
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: Invitro-E.coli
Purity: Greater than 85% as determined by SDS-PAGE.
Length (Amino Acids): 390

Product NumberDescriptionPrice
QP9954-iv-10ug Size: 10 ug, Tag: His $ 1,648.00
QP9954-iv-50ug Size: 50 ug, Tag: His $ 3,068.00
QP9954-iv-100ug Size: 100 ug, Tag: His $ 4,858.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9954-iv-10ug
Recombinant Human 5-hydroxytryptamine receptor 1B Protein General Information
Alternate Names
5-HT1B; 5-HT-1B; 5-HT-1D-beta; HTR1D2; HTR1DB; 5-HT1DB; S12
Curated Database and Bioinformatic Data
Gene SymbolHTR1B
Entrez Gene ID3351
Ensemble Gene IDENSG00000135312
RefSeq Protein Accession(s)NP_000854.1
RefSeq mRNA Accession(s)NM_000863.2
UniProt ID(s)P28222
UniGene ID(s)Hs.123016
HGNC ID(s)HGNC:5287
COSMIC ID Link(s)HTR1B
KEGG Gene ID(s)hsa:3351
PharmGKB ID(s)PA29549
General Description of Recombinant Human 5-hydroxytryptamine receptor 1B Protein.
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Human 5-hydroxytryptamine receptor 1B Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant 5-hydroxytryptamine receptor 1B based upon sequence from Human
Host: QP9954 protein expressed in Invitro-E.coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) 5-hydroxytryptamine receptor 1B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9954.
Bioactivity Data: Untested
Full Length? Full Length Transmembrane Protein
Expression Region: Met1 - Ser390
Amino Acid Sequence: MEEPGAQCAP PPPAGSETWV PQANLSSAPS QNCSAKDYIY QDSISLPWKV LLVMLLALIT LATTLSNAFV IATVYRTRKL HTPANYLIAS LAVTDLLVSI LVMPISTMYT VTGRWTLGQV VCDFWLSSDI TCCTASILHL CVIALDRYWA ITDAVEYSAK RTPKRAAVMI ALVWVFSISI SLPPFFWRQA KAEEEVSECV VNTDHILYTV YSTVGAFYFP TLLLIALYGR IYVEARSRIL KQTPNRTGKR LTRAQLITDS PGSTSSVTSI NSRVPDVPSE SGSPVYVNQV KVRVSDALLE KKKLMAARER KATKTLGIIL GAFIVCWLPF FIISLVMPIC KDACWFHLAI FDFFTWLGYL NSLINPIIYT MSNEDFKQAF HKLIRFKCTS
Purity: Greater than 85% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human 5-hydroxytryptamine receptor 1B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human 5-hydroxytryptamine receptor 1B Protein