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Recombinant Human Beta Defensin 103AB Protein

$ 69.00$ 2,798.00
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SKU: QP5323
Species: Human
Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 45

Product NumberDescriptionPrice
QP5323-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 69.00
QP5323-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 169.00
QP5323-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 439.00
QP5323-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 1,718.00
QP5323-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 2,798.00
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5323-20ug
Recombinant Human Beta Defensin 103AB Protein General Information
Alternate Names
DEFB103A, DEFB103B, Beta Defensin a/b
Curated Database and Bioinformatic Data
Gene SymbolDEFB103AB
Entrez Gene ID414325
Ensemble Gene IDENSG00000176797
RefSeq Protein Accession(s)NP_001075020.1
RefSeq mRNA Accession(s)NM_001081551.3, NM_018661.4, XM_017030192.1
UniProt ID(s)P81534
UniGene ID(s)Hs.283082
HGNC ID(s)HGNC:15967
KEGG Gene ID(s)hsa:414325
PharmGKB ID(s)PA134933952
General Description of Recombinant Human Beta Defensin 103AB Protein .
Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity. BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.

Human Beta Defensin 103AB Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Beta Defensin 103AB based upon sequence from: Human
Host: QP5323 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5323.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Beta Defensin 103AB Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Beta Defensin 103AB Protein