Recombinant Human Fractalkine / CX3CL1 Protein

$ 78.00 – $ 3,138.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5299
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 76

Product Number	Description	Price
QP5299-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 69.00
QP5299-20ug	Size: 20 ug, Tag: Untagged (Native Protein)	$ 169.00
QP5299-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 419.00
QP5299-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 1,718.00
QP5299-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 2,798.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5299-20ug

Recombinant Human Fractalkine / CX3CL1 Protein General Information
Alternate Names
Fractalkine, CX3CL1, ABCD-3, C3Xkine, NTT, SCYD1, CXC3, NTN, fractalkine, CXC3C, neurotactin
Curated Database and Bioinformatic Data
Gene Symbol	CX3CL1
Entrez Gene ID	6376
Ensemble Gene ID	ENSG00000006210
RefSeq Protein Accession(s)	NP_001291321.1
RefSeq mRNA Accession(s)	NM_001304392.1, NM_002996.4
UniProt ID(s)	P78423
UniGene ID(s)	Hs.531668
HGNC ID(s)	HGNC:10647
COSMIC ID Link(s)	CX3CL1
KEGG Gene ID(s)	hsa:6376
PharmGKB ID(s)	PA35577
General Description of Recombinant Human Fractalkine / CX3CL1 Protein .
Fractalkine, also known as CX3CL1, is a cytokine protein containing a CX3C chemokine motif atop a mucin stalk. Fractalkine is produced by non-hemopoietic cells, including neurons and astrocytes. Soluble fractalkine functions as a chemoattractant for T cells and monocytes. Cell-membrane-bound fractalkine, which is induced on activated endothelial cells, promotes leukocyte adhesion. The transmembrane chemokine receptor CX3CR1 mediates the adhesive and chemoattractant functions of fractalkine.

Human Fractalkine / CX3CL1 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Fractalkine / CX3CL1 based upon sequence from: Human

Host: QP5299 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5299.

Bioactivity Data: Human Fractalkine / CX3CL1 inducesÂ Human PBMC chemotaxis (significanty different from control at Human Fractalkine / CX3CL1 concentrations greater than 10-100 ng/ml).

Monomer or Dimer: Monomer

Amino Acid Sequence: QHHGVTKCNI Â TCSKMTSKI PÂ VALLIHYQ QNÂ QASCGKR AIIÂ LETRQH RLFCÂ ADPKE QWVKDÂ AMQH LDRQAAÂ ALT RNG

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Fractalkine / CX3CL1 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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