Recombinant Human GDF11 Protein

$ 69.00$ 3,598.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5369
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 109/218

Product NumberDescriptionPrice
QP5369-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 69.00
QP5369-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 169.00
QP5369-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 469.00
QP5369-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 2,198.00
QP5369-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 3,598.00
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5369-20ug
Recombinant Human GDF11 Protein General Information
Alternate Names
GDF-11, BMP11, BMP-11
Curated Database and Bioinformatic Data
Gene SymbolGDF11
Entrez Gene ID10220
Ensemble Gene IDENSG00000135414
RefSeq Protein Accession(s)NP_005802.1
RefSeq mRNA Accession(s)NM_005811.4, XM_006719194.3
UniProt ID(s)O95390
UniGene ID(s)Hs.600883
HGNC ID(s)HGNC:4216
COSMIC ID Link(s)GDF11
KEGG Gene ID(s)hsa:10220
PharmGKB ID(s)PA28631
General Description of Recombinant Human GDF11 Protein .
Growth differentiation factor 11 (GDF-11), also known as bone morphogenic protein 11 (BMP-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.

Human GDF11 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant GDF11 based upon sequence from: Human
Host: QP5369 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5369.
Bioactivity Data: Alkaline phosphatase activity was demonstrated in ATDC5 cells significantly at concentrations less than 100 ng/ml. Typical ED50 is in the range of 10 ng/ml.
Monomer or Dimer: Dimer
Amino Acid Sequence: NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GDF11 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GDF11 Protein

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