Recombinant Human GDF5 Protein

$ 78.00$ 1,458.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5375
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 121/242

Product NumberDescriptionPrice
QP5375-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 69.00
QP5375-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 169.00
QP5375-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 299.00
QP5375-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 759.00
QP5375-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 1,298.00
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5375-50ug
Recombinant Human GDF5 Protein General Information
Alternate Names
OS5, LAP4, BDA1C, BMP14, CDMP1, LAP-4, SYM1B, SYNS2, BMP-14, GDF-5
Curated Database and Bioinformatic Data
Gene SymbolGDF5
Entrez Gene ID8200
Ensemble Gene IDENSG00000125965
RefSeq Protein Accession(s)NP_000548.2
RefSeq mRNA Accession(s)NM_000557.4, NM_001319138.1, XM_011529075.2
UniProt ID(s)P43026
UniGene ID(s)Hs.1573
HGNC ID(s)HGNC:4220
COSMIC ID Link(s)GDF5
KEGG Gene ID(s)hsa:8200
PharmGKB ID(s)PA28635
General Description of Recombinant Human GDF5 Protein .
Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenic protein (BMP) and transforming growth factor beta (TGF-?) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is expressed in the central nervous system and promotes the survival of dopaminergic neurons in animal models of Parkinson's disease. GDF-5 is also important during chondrogenesis and chondrocyte differentiation.

Human GDF5 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant GDF5 based upon sequence from: Human
Host: QP5375 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5375.
Bioactivity Data: Alkaline phosphatase activity in ATDC5 cells significantly induced by less than 1.2 ug/ml, or activity of at least 8.3 x 10^2 units/mg,

(typical ED50 is ?

Monomer or Dimer: Dimer
Amino Acid Sequence: MAPLATRQGK RPSKNLKARC SRKALHVNFK DMGWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFID SANNVVYKQY EDMVVESCGC R
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GDF5 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GDF5 Protein

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