Recombinant Human Oncostatin M / OSM Protein

$ 69.00$ 4,898.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5367
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 210

Product NumberDescriptionPrice
QP5367-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 69.00
QP5367-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 169.00
QP5367-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 639.00
QP5367-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 2,978.00
QP5367-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 4,898.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5367-10ug
Recombinant Human Oncostatin M / OSM Protein General Information
Alternate Names
Oncostatin M, OSM, OncoM
Curated Database and Bioinformatic Data
Gene SymbolOSM
Entrez Gene ID5008
Ensemble Gene IDENSG00000099985
RefSeq Protein Accession(s)NP_001306037.1
RefSeq mRNA Accession(s)NM_001319108.1, NM_020530.5
UniProt ID(s)P13725
UniGene ID(s)Hs.248156
HGNC ID(s)HGNC:8506
COSMIC ID Link(s)OSM
KEGG Gene ID(s)hsa:5008
PharmGKB ID(s)PA32836
General Description of Recombinant Human Oncostatin M / OSM Protein .
Oncostatin M (OSM) is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. The Type-I and Type-II OSM receptors are located on the cell surface of endothelial and tumor cells, contain the glycoprotein 130 (gp130) subunit, and activate the JAK/STAT signaling pathway. OSM functions to inhibit tumor cell proliferation, induce liver stem cell maturation, regulate cytokine production during hematopoiesis and inflammation, stimulate bone formation, and promote nervous system development.

Human Oncostatin M / OSM Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Oncostatin M / OSM based upon sequence from: Human
Host: QP5367 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5367.
Bioactivity Data: TF-1 cell proliferation was significantly induced by less than 4 ng/ml of Human Oncostatin M / OSM (minimum activity of at least 2.5 x 10^5 units/mg).
Monomer or Dimer: Monomer
Amino Acid Sequence: MAAIGSCSKE  YRVLLGQLQ K QTDLMQDT SR LLDPYIR IQG LDVPKL REHC RERPG AFPSE ETLR GLGRRG FLQ TLNATLGCVL HRLADLE QR LPKAQDLE R SGLNIEDLE  KLQMARPNIL  GLRNNIYCM A QLLDNSDT AE PTKAGRG ASQ PPTPTP ASDA FQRKL EGCRFLHGYH RFMHS VGRV FSKWGE SPN RSRRHSP HQ ALRKGVRR
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Oncostatin M / OSM Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Oncostatin M / OSM Protein

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