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Recombinant Human Pleiotrophin / PTN / HB-GAM Protein

$ 78.00$ 3,138.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5365
Species: Human
Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 137

Product NumberDescriptionPrice
QP5365-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 69.00
QP5365-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 169.00
QP5365-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 419.00
QP5365-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 1,718.00
QP5365-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 2,798.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5365-20ug
Recombinant Human Pleiotrophin / PTN / HB-GAM Protein General Information
Alternate Names
Pleiotrophin, PTN, HB-GAM, HBGF-8, NEGF1, HBNF, OSF-1, HB-GAM, HBGF8, HBNF-1, HARP, HBBM
Curated Database and Bioinformatic Data
Gene SymbolPTN
Entrez Gene ID5764
Ensemble Gene IDENSG00000105894
RefSeq Protein Accession(s)NP_001308315.1
RefSeq mRNA Accession(s)NM_001321386.2, NM_001321387.2, NM_002825.6
UniProt ID(s)P21246
UniGene ID(s)Hs.371249
HGNC ID(s)HGNC:9630
COSMIC ID Link(s)PTN
KEGG Gene ID(s)hsa:5764
PharmGKB ID(s)PA33974
General Description of Recombinant Human Pleiotrophin / PTN / HB-GAM Protein .
Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis. PTN binds with low affinity to the cell surface receptor nucleolin to inhibit HIV-1 infection. PNT can also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.

Human Pleiotrophin / PTN / HB-GAM Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Pleiotrophin / PTN / HB-GAM based upon sequence from: Human
Host: QP5365 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5365.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRTGS LKRALHNAEC QKTVTISKPC GKLTKPKPQA ESKKKKKEGK KQEKMLD
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Pleiotrophin / PTN / HB-GAM Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Pleiotrophin / PTN / HB-GAM Protein