Recombinant Human TNFSF10 / TRAIL / APO-2L Protein

$ 69.00$ 1,298.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5244
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 90 as determined by SDS-PAGE.
Length (Amino Acids): 168

Product NumberDescriptionPrice
QP5244-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 69.00
QP5244-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 169.00
QP5244-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 299.00
QP5244-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 759.00
QP5244-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 1,298.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5244-50ug
Recombinant Human TNFSF10 / TRAIL / APO-2L Protein General Information
Alternate Names
TNFSF10, TRAIL, APO-2L, Tnlg6a, Trail, TL2, Ly81, AI448571, APO-2L, A330042I21Rik
Curated Database and Bioinformatic Data
Gene SymbolTNFSF10
Entrez Gene ID8743
Ensemble Gene IDENSG00000121858
RefSeq Protein Accession(s)NP_001177871.1
RefSeq mRNA Accession(s)NM_001190942.1, NM_003810.3
UniProt ID(s)P50591
UniGene ID(s)Hs.478275
HGNC ID(s)HGNC:11925
COSMIC ID Link(s)TNFSF10
KEGG Gene ID(s)hsa:8743
PharmGKB ID(s)PA36618
General Description of Recombinant Human TNFSF10 / TRAIL / APO-2L Protein .
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) family of cytokines. TRAIL is widely produced by a variety of cell types including tumor cells, smooth muscle of the lung and spleen, cerebellar glial cells, and thyroid follicular cells. TRAIL is a cytotoxic protein that induces apoptosis in tumor cells through the activation of the death receptors DR4 and DR5. TRAIL also binds the neutralizing decoy receptors, DcR1 and DcR2. Human TRAIL is active on mouse cells.

Human TNFSF10 / TRAIL / APO-2L Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant TNFSF10 / TRAIL / APO-2L based upon sequence from: Human
Host: QP5244 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5244.
Bioactivity Data: Human TNFSF10 / TRAIL / APO-2L induces RPMI-8226 cell proliferation (typical ED50 is ? 15 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TNFSF10 / TRAIL / APO-2L Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TNFSF10 / TRAIL / APO-2L Protein

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