Recombinant Mouse IL-31 / IL31 Protein

$ 69.00$ 4,898.00
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SKU: QP5477
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 141

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Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP5477-2ug
Recombinant Mouse IL-31 / IL31 Protein General Information
Alternate Names
IL-31, IL31, 1700013B14Rik
Curated Database and Bioinformatic Data
Gene SymbolIL31
Entrez Gene ID76399
Ensemble Gene IDENSMUSG00000029437
RefSeq Protein Accession(s)NP_083870.1
RefSeq mRNA Accession(s)NM_029594.1, XM_006530498.1
UniProt ID(s)Q6EAL8
UniGene ID(s)Mm.75049
COSMIC ID Link(s)IL31
KEGG Gene ID(s)mmu:76399
General Description of Recombinant Mouse IL-31 / IL31 Protein .
Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

Mouse IL-31 / IL31 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-31 / IL31 based upon sequence from Mouse
Host: QP5477 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5477.
Bioactivity Data: Mouse IL-31 / IL31 induces IL-8 production in human PBMCs which was detected via ELISA (typical ED50 is ? 25 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse IL-31 / IL31 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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