Recombinant Mouse PDGF-B Protein

$ 69.00$ 3,598.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5465
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 110/220

Product NumberDescriptionPrice
QP5465-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 69.00
QP5465-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 169.00
QP5465-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 469.00
QP5465-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 2,198.00
QP5465-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 3,598.00
Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP5465-2ug
Recombinant Mouse PDGF-B Protein General Information
Alternate Names
PDGF-B, IBGC5, PDGF2, SSV, PDGF-2, SIS, c-sis
Curated Database and Bioinformatic Data
Gene SymbolPDGFB
Entrez Gene ID18591
RefSeq Protein Accession(s)NP_035187.2
RefSeq mRNA Accession(s)NM_011057.3, XM_017316502.1
UniProt ID(s)P31240
UniGene ID(s)Mm.144089
COSMIC ID Link(s)PDGFB
KEGG Gene ID(s)mmu:18591
General Description of Recombinant Mouse PDGF-B Protein .
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF?), transforming growth factor beta (TGF-?), and epidermal growth factor (EGF) signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Mouse PDGF-B Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant PDGF-B based upon sequence from Mouse
Host: QP5465 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5465.
Bioactivity Data: 3T3 cell proliferation significantly induced by less than 2 ng/ml of Mouse PDGF-B.
Monomer or Dimer: Dimer
Amino Acid Sequence: MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse PDGF-B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium citrate, pH 3.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse PDGF-B Protein

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