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Recombinant Human sIL 6R Protein

$ 98.00$ 3,138.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP13504
Species: Human
Applications: See Application Notes
Available Tags: His
Available Hosts: E. Coli
Purity: Greater than 90.0% as determined by SDS-PAGE.
Length (Amino Acids):

Product NumberDescriptionPrice
QP13504-5ug Size: 5 ug, Tag: His $ 98.00
QP13504-20ug Size: 20 ug, Tag: His $ 148.00
QP13504-1mg Size: 1 mg, Tag: His $ 3,138.00
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In Stock
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP13504-5ug
Recombinant Human sIL 6R General Information
sIL 6R  protein 3D structural model from Catalog of Somatic Mutations in Cancer originally published in the paper COSMIC: somatic cancer genetics at high-resolution
Alternate Names
IL6R-alpha, CD126, IL-6R 1, CD126 antigen, IL6RA, Interleukin 6 receptor, Interleukin 6 receptor alpha subunit, Interleukin-6 receptor alpha chain precursor, B cell stimulatory factor-2,Membrane glycoprotein 80, gp80, IL-6R, MGC104991.
Molecular Weight
42.25 kDa
Chromosomal Location
q21.3 on chromosome 1
Curated Database and Bioinformatic Data
Gene SymbolIL6R
Entrez Gene ID3570
UniProt ID(s)P08887
COSMIC ID Link(s)IL6R
KEGG Gene ID(s)hsa:3570
General Description of Recombinant Human sIL 6R.
Human sIL-6R produced in E. Coli is a single, non-glycosylated polypeptide chain containing 338 amino acids (20-357) corresponding to the mature IL-6R protein, having a molecular weight of 42.25 kDa, with an amino terminal hexahistidine tag. The sIL6R is purified by using an optimized multi-step FPLC method for maximum separation from contaminants.

Human sIL 6R Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant sIL 6R based upon sequence from Human
Host: QP13504 protein expressed in E. Coli.
Available Tags: His
Protein Construction: A cDNA sequence encoding the sequence of sIL 6R was constructred and used to recombinantly synthesize the protein.
Recommended Applications: See Application Notes
Application Notes: Please contact us for application specific information for QP13504.
Bioactivity Data: Untested
Amino Acid Sequence: MLAVGCALLA ALLAAPGAAL APRRCPAQEV ARGVLTSLPG DSVTLTCPGV EPEDNATVHW VLRKPAAGSH PSRWAGMGRR LLLRSVQLHD SGNYSCYRAG RPAGTVHLLV DVPPEEPQLS CFRKSPLSNV VCEWGPRSTP SLTTKAVLLV RKFQNSPAED FQEPCQYSQE SQKFSCQLAV PEGDSSFYIV SMCVASSVGS KFSKTQTFQG CGILQPDPPA NITVTAVARN PRWLSVTWQD PHSWNSSFYR LRFELRYRAE RSKTFTTWMV KDLQHHCVIH DAWSGLRHVV QLRAQEEFGQ GEWSEWSPEA MGTPWTESRS PPAENEVSTP MQALTTNKDD DNILFRDSAN ATSLPVQDSS SVPLPTFLVA GGSLAFGTLL CIAIVLRFKK TWKLRALKEG KTSMHPPYSL GQLVPERPRP TPVLVPLISP PVSPSSLGSD NTSSHNRPDA RDPRSPYDIS NTDYFFPR
Purity: Greater than 90.0% as determined by SDS-PAGE.
Reconstitution Instructions: |||
Endotoxin Levels: Not Determined. Testing recommended prior to use in cell culture and can be performed upon request.
Buffer: CD126 His-Tag protein is supplied in 20mM Tris-HCl, pH 8.0, 0.8M Urea & 50% glycerol.
Storage Conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Physical Appearance: Sterile Filtered clear solution.

Selected References

IL-6 loss causes ventriculardysfunction, fibrosis, reduced capillary density, and dramatically alters thecell populations of the developing and adult heartPublication: American Journal of Physiology-Heart andCirculatory Physiology 296.5 (2009): H1694-H1704.Link: http://ajpheart.physiology.org/content/296/5/H1694.short

Limitations and Performance Guarantee

enQuire Bio's products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human sIL 6R Protein