Human Centrin-3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Centrin-3 based upon sequence from Human
Host: QP5821 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Centrin-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5821.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ile167
Amino Acid Sequence: MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Centrin-3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Centrin-3 Protein General Information | |
|---|---|
| Alternate Names | |
| CDC31, CEN3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CETN3 |
| Entrez Gene ID | 1070 |
| Ensemble Gene ID | ENSG00000153140 |
| RefSeq Protein Accession(s) | NP_001284697.1 |
| RefSeq mRNA Accession(s) | NM_001297768.1, NM_004365.3 |
| UniProt ID(s) | O15182 |
| UniGene ID(s) | Hs.591767 |
| HGNC ID(s) | HGNC:1868 |
| COSMIC ID Link(s) | CETN3 |
| KEGG Gene ID(s) | hsa:1070 |
| PharmGKB ID(s) | PA26421 |
| General Description of Recombinant Human Centrin-3 Protein. | |
| Plays a fundamental role in microtubule-organizing center structure and function. Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery |
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Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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