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Recombinant Human Suppressor of cytokine signaling 2 Protein

$ 228.00$ 2,468.00
Please Select A Product To View The SKU.

SKU: QP6712
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 199

Size
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Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP6712-ec-10ug
Recombinant Human Suppressor of cytokine signaling 2 Protein General Information
Alternate Names
SOCS-2, Cish2, SSI2, STATI2, SSI-2, CIS2
Curated Database and Bioinformatic Data
Gene SymbolSOCS2
Entrez Gene ID8835
Ensemble Gene IDENSG00000120833
RefSeq Protein Accession(s)NP_001257396.1
RefSeq mRNA Accession(s)NM_001270467.1, NM_001270468.1, NM_001270469.1, NM_001270470.1, NM_001270471.1, NM_003877.4, XM_017020156.1
UniProt ID(s)O14508
UniGene ID(s)Hs.485572
HGNC ID(s)HGNC:19382
COSMIC ID Link(s)SOCS2
KEGG Gene ID(s)hsa:8835
PharmGKB ID(s)PA128394542
General Description of Recombinant Human Suppressor of cytokine signaling 2 Protein.
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Human Suppressor of cytokine signaling 2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Suppressor of cytokine signaling 2 based upon sequence from Human
Host: QP6712 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Suppressor of cytokine signaling 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6712.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL YLTKPLYTSA PSLQHLCRLT INKCTGAIWG LPLPTRLKDY LEEYKFQV
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Suppressor of cytokine signaling 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Suppressor of cytokine signaling 2 Protein