SDS-PAGE separation of QP6817 followed by commassie total protein stain results in a primary band consistent with reported data for TNFSF10 / TRAIL / APO-2L. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6817 followed by commassie total protein stain results in a primary band consistent with reported data for TNFSF10 / TRAIL / APO-2L. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human TNFSF10 / TRAIL / APO-2L Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6817
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 243

Size
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Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP6817-ec-10ug
Recombinant Human TNFSF10 / TRAIL / APO-2L Protein General Information
Alternate Names
TNFSF10, TRAIL, APO-2L, Tnlg6a, Trail, TL2, Ly81, AI448571, APO-2L, A330042I21Rik
Curated Database and Bioinformatic Data
Gene SymbolTNFSF10
Entrez Gene ID8743
Ensemble Gene IDENSG00000121858
RefSeq Protein Accession(s)NP_001177871.1
RefSeq mRNA Accession(s)NM_001190942.1, NM_003810.3
UniProt ID(s)P50591
UniGene ID(s)Hs.478275
HGNC ID(s)HGNC:11925
COSMIC ID Link(s)TNFSF10
KEGG Gene ID(s)hsa:8743
PharmGKB ID(s)PA36618
General Description of Recombinant Human TNFSF10 / TRAIL / APO-2L Protein.
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

Human TNFSF10 / TRAIL / APO-2L Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant TNFSF10 / TRAIL / APO-2L based upon sequence from Human
Host: QP6817 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TNFSF10 / TRAIL / APO-2L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6817.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Thr39 - Gly281
Amino Acid Sequence: TNELKQMQDK YSKSGIACFL KEDDSYWDPN DEESMNSPCW QVKWQLRQLV RKMILRTSEE TISTVQEKQQ NISPLVRERG PQRVAAHITG TRGRSNTLSS PNSKNEKALG RKINSWESSR SGHSFLSNLH LRNGELVIHE KGFYYIYSQT YFRFQEEIKE NTKNDKQMVQ YIYKYTSYPD PILLMKSARN SCWSKDAEYG LYSIYQGGIF ELKENDRIFV SVTNEHLIDM DHEASFFGAF LVG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TNFSF10 / TRAIL / APO-2L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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