SDS-PAGE separation of QP6884 followed by commassie total protein stain results in a primary band consistent with reported data for WD repeat-containing protein 5. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6884 followed by commassie total protein stain results in a primary band consistent with reported data for WD repeat-containing protein 5. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human WD repeat-containing protein 5 Protein

$ 148.00$ 1,678.00
Please Select A Product To View The SKU.

SKU: QP6884
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 333

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Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP6884-ec-10ug
Recombinant Human WD repeat-containing protein 5 Protein General Information
Alternate Names
CFAP89, SWD3, BIG-3
Curated Database and Bioinformatic Data
Gene SymbolWDR5
Entrez Gene ID11091
Ensemble Gene IDENSG00000196363
RefSeq Protein Accession(s)NP_060058.1
RefSeq mRNA Accession(s)NM_017588.2, NM_052821.3, XM_005272163.1
UniProt ID(s)P61964
UniGene ID(s)Hs.397638
HGNC ID(s)HGNC:12757
COSMIC ID Link(s)WDR5
KEGG Gene ID(s)hsa:11091
PharmGKB ID(s)PA37361
General Description of Recombinant Human WD repeat-containing protein 5 Protein.
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Human WD repeat-containing protein 5 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant WD repeat-containing protein 5 based upon sequence from Human
Host: QP6884 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) WD repeat-containing protein 5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6884.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 - Cys334
Amino Acid Sequence: ATEEKKPETE AARAQPTPSS SATQSKPTPV KPNYALKFTL AGHTKAVSSV KFSPNGEWLA SSSADKLIKI WGAYDGKFEK TISGHKLGIS DVAWSSDSNL LVSASDDKTL KIWDVSSGKC LKTLKGHSNY VFCCNFNPQS NLIVSGSFDE SVRIWDVKTG KCLKTLPAHS DPVSAVHFNR DGSLIVSSSY DGLCRIWDTA SGQCLKTLID DDNPPVSFVK FSPNGKYILA ATLDNTLKLW DYSKGKCLKT YTGHKNEKYC IFANFSVTGG KWIVSGSEDN LVYIWNLQTK EIVQKLQGHT DVVISTACHP TENIIASAAL ENDKTIKLWK SDC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human WD repeat-containing protein 5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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