SDS-PAGE separation of QP7857 followed by commassie total protein stain results in a primary band consistent with reported data for P4HB / ERBA2L. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Chinese Hamster P4HB / ERBA2L Protein

$ 328.00 – $ 2,958.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP7857
Species: Chinese Hamster
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 490

Product Number	Description	Price
QP7857-ye-10ug	Size: 10 ug, Tag: His	$ 328.00
QP7857-ye-50ug	Size: 50 ug, Tag: His	$ 458.00
QP7857-ye-100ug	Size: 100 ug, Tag: His	$ 798.00
QP7857-ye-200ug	Size: 200 ug, Tag: His	$ 1,318.00
QP7857-ye-500ug	Size: 500 ug, Tag: His	$ 1,858.00
QP7857-ye-1mg	Size: 1 mg, Tag: His	$ 2,958.00
QP7857-ec-100ug	Size: 100 ug, Tag: His	$ 728.00
QP7857-ec-1mg	Size: 1 mg, Tag: His	$ 2,468.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP7857-ye-10ug

Recombinant Chinese Hamster P4HB / ERBA2L Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	P4hb
Entrez Gene ID	100689433
RefSeq Protein Accession(s)	NP_001233622.1
RefSeq mRNA Accession(s)	NM_001246693.1
UniProt ID(s)	Q8R4U2
COSMIC ID Link(s)	P4hb
KEGG Gene ID(s)	cge:100689433
General Description of Recombinant Chinese Hamster P4HB / ERBA2L Protein.
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.

Chinese Hamster P4HB / ERBA2L Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant P4HB / ERBA2L based upon sequence from: Chinese Hamster

Host: QP7857 protein expressed in E.coli, Yeast..

Tag: His

Protein Construction: A DNA sequence encoding the Chinese hamster P4HB / ERBA2L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP7857.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Asp20 - Leu509

Amino Acid Sequence: DAPEEEDNVL VLKKSNFAEA LAAHNYLLVE FYAPWCGHCK ALAPEYAKAA AKLKAEGSEI RLAKVDATEE SDLAQQYGVR GYPTIKFFKN GDTASPKEYT AGREADDIVN WLKKRTGPAA TTLSDTAAAE TLIDSSEVAV IGFFKDVESD SAKQFLLAAE AVDDIPFGIT SNSGVFSKYQ LDKDGVVLFK KFDEGRNNFE GEVTKEKLLD FIKHNQLPLV IEFTEQTAPK IFGGEIKTHI LLFLPKSVSD YDGKLGNFKK AAEGFKGKIL FIFIDSDHTD NQRILEFFGL KKEECPAVRL ITLEEEMTKY KPESDELTAE KITEFCHRFL EGKIKPHLMS QELPEDWDKQ PVKVLVGKNF EEVAFDEKKN VFVEFYAPWC GHCKQLAPIW DKLGETYKDH ENIIIAKMDS TANEVEAVKV HSFPTLKFFP ATADRTVIDY NGERTLDGFK KFLESGGQDG AGDDDDVDLE EALEPDMEED DDQKAVKDEL

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Chinese Hamster P4HB / ERBA2L Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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