SDS-PAGE separation of QP8876 followed by commassie total protein stain results in a primary band consistent with reported data for TIMP-1 / TIMP1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat TIMP-1 / TIMP1 Protein

$ 648.00 – $ 2,768.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP8876
Species: Rat
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 194

Product Number	Description	Price
QP8876-ec-100ug	Size: 100 ug, Tag: His	$ 578.00
QP8876-ec-1mg	Size: 1 mg, Tag: His	$ 2,468.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8876-ec-10ug

Recombinant Rat TIMP-1 / TIMP1 Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	Timp1
Entrez Gene ID	116510
Ensemble Gene ID	ENSRNOG00000010208
RefSeq Protein Accession(s)	NP_446271.1
RefSeq mRNA Accession(s)	NM_053819.1, XM_006256608.2
UniProt ID(s)	P30120
UniGene ID(s)	Rn.25754
COSMIC ID Link(s)	Timp1
KEGG Gene ID(s)	rno:116510
General Description of Recombinant Rat TIMP-1 / TIMP1 Protein.
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates th by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity.

Rat TIMP-1 / TIMP1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant TIMP-1 / TIMP1 based upon sequence from: Rat

Host: QP8876 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) TIMP-1 / TIMP1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8876.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Cys24 - Ala217

Amino Acid Sequence: CSCAPTHPQT AFCNSDLVIR AKFMGSPEII ETTLYQRYEI KMTKMLKGFD AVGNATGFRF AYTPAMESLC GYVHKSQNRS EEFLIAGRLR NGNLHITACS FLVPWHNLSP AQQKAFVKTY SAGCGVCTVF PCSAIPCKLE SDSHCLWTDQ ILMGSEKGYQ SDHFACLPRN PDLCTWQYLG VSMTRSLPLA KAEA

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Rat TIMP-1 / TIMP1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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