PDF DatasheetHuman Allograft inflammatory factor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Allograft inflammatory factor 1 based upon sequence from Human
Host: QP5630 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Allograft inflammatory factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5630.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser2 – Pro147
Amino Acid Sequence: SQTRDLQGGK AFGLLKAQQE ERLDEINKQF LDDPKYSSDE DLPSKLEGFK EKYMEFDLNG NGDIDIMSLK RMLEKLGVPK THLELKKLIG EVSSGSGETF SYPDFLRMML GKRSAILKMI LMYEEKAREK EKPTGPPAKK AISELP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Allograft inflammatory factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Allograft inflammatory factor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| IRT-1, IBA1, IRT1, AIF-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Aif1 |
| Entrez Gene ID | 199 |
| Ensemble Gene ID | ENSG00000204472 |
| RefSeq Protein Accession(s) | NP_001305899.1 |
| RefSeq mRNA Accession(s) | NM_001318970.1, NM_001623.4, NM_032955.2, XM_017010332.1 |
| UniProt ID(s) | P55008 |
| UniGene ID(s) | Hs.76364 |
| HGNC ID(s) | HGNC:352 |
| COSMIC ID Link(s) | Aif1 |
| KEGG Gene ID(s) | hsa:199 |
| PharmGKB ID(s) | PA24646 |
| General Description of Recombinant Human Allograft inflammatory factor 1 Protein. | |
| Actin-binding protein that enhances mbrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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