PDF DatasheetHuman Apolipoprotein C-III Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Apolipoprotein C-III based upon sequence from Human
Host: QP5666 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Apolipoprotein C-III, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5666.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser21 – Ala99
Amino Acid Sequence: SEAEDASLLS FMQGYMKHAT KTAKDALSSV QESQVAQQAR GWVTDGFSSL KDYWSTVKDK FSEFWDLDPE VRPTSAVAA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Apolipoprotein C-III Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Apolipoprotein C-III Protein General Information | |
|---|---|
| Alternate Names | |
| APOCIII, HALP2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | APOC3 |
| Entrez Gene ID | 345 |
| Ensemble Gene ID | ENSG00000110245 |
| RefSeq Protein Accession(s) | NP_000031.1 |
| RefSeq mRNA Accession(s) | NM_000040.1 |
| UniProt ID(s) | P02656 |
| UniGene ID(s) | Hs.73849 |
| HGNC ID(s) | HGNC:610 |
| COSMIC ID Link(s) | APOC3 |
| KEGG Gene ID(s) | hsa:345 |
| PharmGKB ID(s) | PA53 |
| General Description of Recombinant Human Apolipoprotein C-III Protein. | |
| Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assbly and secretion; Extracellular domainly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by rnant receptors. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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