PDF DatasheetHuman CLIC4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CLIC4 based upon sequence from Human
Host: QP5838 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CLIC4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5838.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys253
Amino Acid Sequence: MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR LTK
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CLIC4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CLIC4 Protein General Information | |
|---|---|
| Alternate Names | |
| CLIC4, MTCLIC, p64H1, H1, huH1, CLIC4L | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CLIC4 |
| Entrez Gene ID | 25932 |
| Ensemble Gene ID | ENSG00000169504 |
| RefSeq Protein Accession(s) | NP_039234.1 |
| RefSeq mRNA Accession(s) | NM_013943.2 |
| UniProt ID(s) | Q9Y696 |
| UniGene ID(s) | Hs.440544 |
| HGNC ID(s) | HGNC:13518 |
| COSMIC ID Link(s) | CLIC4 |
| KEGG Gene ID(s) | hsa:25932 |
| PharmGKB ID(s) | PA26591 |
| General Description of Recombinant Human CLIC4 Protein. | |
| Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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