PDF DatasheetHuman CRADD / RAIDD Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CRADD / RAIDD based upon sequence from Human
Host: QP5865 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CRADD / RAIDD, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5865.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Glu199
Amino Acid Sequence: MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CRADD / RAIDD Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CRADD / RAIDD Protein General Information | |
|---|---|
| Alternate Names | |
| CRADD, RAIDD, RAIDD, MRT34 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CRADD |
| Entrez Gene ID | 8738 |
| Ensemble Gene ID | ENSG00000169372 |
| RefSeq Protein Accession(s) | NP_001307028.1 |
| RefSeq mRNA Accession(s) | NM_001320099.1, NM_001320100.1, NM_001320101.1, NM_003805.4, XM_017020144.1 |
| UniProt ID(s) | P78560 |
| UniGene ID(s) | Hs.38533 |
| HGNC ID(s) | HGNC:2340 |
| COSMIC ID Link(s) | CRADD |
| KEGG Gene ID(s) | hsa:8738 |
| PharmGKB ID(s) | PA26860 |
| General Description of Recombinant Human CRADD / RAIDD Protein. | |
| Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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