PDF DatasheetHuman TIM3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TIM3 based upon sequence from Human
Host: QP6145 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TIM3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6145.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ser22 – Gly202
Amino Acid Sequence: SEVEYRAEVG QNAYLPCFYT PAAPGNLVPV CWGKGACPVF ECGNVVLRTD ERDVNYWTSR YWLNGDFRKG DVSLTIENVT LADSGIYCCR IQIPGIMNDE KFNLKLVIKP AKVTPAPTRQ RDFTAAFPRM LTTRGHGPAE TQTLGSLPDI NLTQISTLAN ELRDSRLAND LRDSGATIRI G
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TIM3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TIM3 Protein General Information | |
|---|---|
| Alternate Names | |
| TIM3, CD366, KIM-3, TIMD-3, Tim-3, HAVcr-2, TIM3, TIMD3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HAVCR2 |
| Entrez Gene ID | 84868 |
| Ensemble Gene ID | ENSG00000135077 |
| RefSeq Protein Accession(s) | NP_116171.3 |
| RefSeq mRNA Accession(s) | NM_032782.4 |
| UniProt ID(s) | Q8TDQ0 |
| UniGene ID(s) | Hs.710500 |
| HGNC ID(s) | HGNC:18437 |
| COSMIC ID Link(s) | HAVCR2 |
| KEGG Gene ID(s) | hsa:84868 |
| PharmGKB ID(s) | PA134883425 |
| General Description of Recombinant Human TIM3 Protein. | |
| Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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