PDF DatasheetHuman Histone H2A type 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone H2A type 1 based upon sequence from Human
Host: QP6158 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone H2A type 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6158.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 – Lys130
Amino Acid Sequence: SGRGKQGGKA RAKAKTRSSR AGLQFPVGRV HRLLRKGNYA ERVGAGAPVY LAAVLEYLTA EILELAGNAA RDNKKTRIIP RHLQLAIRND EELNKLLGKV TIAQGGVLPN IQAVLLPKKT ESHHKAKGK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Histone H2A type 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone H2A type 1 Protein General Information | |
|---|---|
| Alternate Names | |
| H2AFC, H2A/c, H2AFD, H2A/d, H2A/n, H2A.1, H2AFN, dJ193B12.1, H2A.1b, H2AFP, pH2A/f, H2A/p, H2AG, H2AFI, dJ193B12.9, H2A.i, H2A/i | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HIST1H2AG |
| Entrez Gene ID | 8329 |
| Ensemble Gene ID | ENSG00000196747 |
| RefSeq Protein Accession(s) | NP_003500.1 |
| RefSeq mRNA Accession(s) | NM_003509.2, NM_003510.2, NM_003511.2, NM_003514.2, NM_021064.4 |
| UniProt ID(s) | P0C0S8 |
| UniGene ID(s) | Hs.134999 |
| HGNC ID(s) | HGNC:4737 |
| COSMIC ID Link(s) | HIST1H2AG |
| KEGG Gene ID(s) | hsa:8329 |
| PharmGKB ID(s) | PA29114 |
| General Description of Recombinant Human Histone H2A type 1 Protein. | |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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