PDF DatasheetHuman IL-1 beta / IL1B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL-1 beta / IL1B based upon sequence from Human
Host: QP6214 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL-1 beta / IL1B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6214.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala117 – Ser269
Amino Acid Sequence: APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human IL-1 beta / IL1B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL-1 beta / IL1B Protein General Information | |
|---|---|
| Alternate Names | |
| IL-1 beta, IL1B, IL-1, IL1-BETA, IL1F2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL1B |
| Entrez Gene ID | 3553 |
| Ensemble Gene ID | ENSG00000125538 |
| RefSeq Protein Accession(s) | NP_000567.1 |
| RefSeq mRNA Accession(s) | NM_000576.2 |
| UniProt ID(s) | P01584 |
| UniGene ID(s) | Hs.126256 |
| HGNC ID(s) | HGNC:5992 |
| COSMIC ID Link(s) | IL1B |
| KEGG Gene ID(s) | hsa:3553 |
| PharmGKB ID(s) | PA29808 |
| General Description of Recombinant Human IL-1 beta / IL1B Protein. | |
| Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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