PDF DatasheetHuman C-X-C chemokine receptor type 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C-X-C chemokine receptor type 2 based upon sequence from Human
Host: QP6229 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) C-X-C chemokine receptor type 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6229.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Glu40
Amino Acid Sequence: MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human C-X-C chemokine receptor type 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-X-C chemokine receptor type 2 Protein General Information | |
|---|---|
| Alternate Names | |
| CD182, CMKAR2, IL8R2, CDw128b, IL8RB, IL8RA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCR2 |
| Entrez Gene ID | 3579 |
| Ensemble Gene ID | ENSG00000180871 |
| RefSeq Protein Accession(s) | NP_001161770.1 |
| RefSeq mRNA Accession(s) | NM_001168298.1, NM_001557.3, XM_005246530.3, XM_017003990.1, XM_017003991.1, XM_017003992.1 |
| UniProt ID(s) | P25025 |
| UniGene ID(s) | Hs.846 |
| HGNC ID(s) | HGNC:6027 |
| COSMIC ID Link(s) | CXCR2 |
| KEGG Gene ID(s) | hsa:3579 |
| PharmGKB ID(s) | PA29843 |
| General Description of Recombinant Human C-X-C chemokine receptor type 2 Protein. | |
| Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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