PDF DatasheetHuman Nuclear transport factor 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nuclear transport factor 2 based upon sequence from Human
Host: QP6442 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Nuclear transport factor 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6442.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gly127
Amino Acid Sequence: MGDKPIWEQI GSSFIQHYYQ LFDNDRTQLG AIYIDASCLT WEGQQFQGKA AIVEKLSSLP FQKIQHSITA QDHQPTPDSC IISMVVGQLK ADEDPIMGFH QMFLLKNIND AWVCTNDMFR LALHNFG
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Nuclear transport factor 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Nuclear transport factor 2 Protein General Information | |
|---|---|
| Alternate Names | |
| NTF2, NTF-2, PP15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NUTF2 |
| Entrez Gene ID | 10204 |
| Ensemble Gene ID | ENSG00000102898 |
| RefSeq Protein Accession(s) | NP_001308967.1 |
| RefSeq mRNA Accession(s) | NM_001322038.1, NM_001322039.1, NM_001322040.1, NM_001322041.1, NM_005796.2 |
| UniProt ID(s) | P61970 |
| UniGene ID(s) | Hs.356630 |
| HGNC ID(s) | HGNC:13722 |
| COSMIC ID Link(s) | NUTF2 |
| KEGG Gene ID(s) | hsa:10204 |
| PharmGKB ID(s) | PA38365 |
| General Description of Recombinant Human Nuclear transport factor 2 Protein. | |
| Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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