PDF DatasheetHuman Proteasome subunit alpha type-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Proteasome subunit alpha type-1 based upon sequence from Human
Host: QP6543 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Proteasome subunit alpha type-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6543.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Asp251
Amino Acid Sequence: MFRNQYDNDV TVWSPQGRIH QIEYAMEAVK QGSATVGLKS KTHAVLVALK RAQSELAAHQ KKILHVDNHI GISIAGLTAD ARLLCNFMRQ ECLDSRFVFD RPLPVSRLVS LIGSKTQIPT QRYGRRPYGV GLLIAGYDDM GPHIFQTCPS ANYFDCRAMS IGARSQSART YLERHMSEFM ECNLNELVKH GLRALRETLP AEQDLTTKNV SIGIVGKDLE FTIYDDDDVS PFLEGLEERP QRKAQPAQPA D
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Proteasome subunit alpha type-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Proteasome subunit alpha type-1 Protein General Information | |
|---|---|
| Alternate Names | |
| NU, HC2, HEL-S-275, PROS30 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PSMA1 |
| Entrez Gene ID | 5682 |
| Ensemble Gene ID | ENSG00000129084 |
| RefSeq Protein Accession(s) | NP_002777.1 |
| RefSeq mRNA Accession(s) | NM_002786.3, NM_148976.2 |
| UniProt ID(s) | P25786 |
| UniGene ID(s) | Hs.102798 |
| HGNC ID(s) | HGNC:9530 |
| COSMIC ID Link(s) | PSMA1 |
| KEGG Gene ID(s) | hsa:5682 |
| PharmGKB ID(s) | PA33875 |
| General Description of Recombinant Human Proteasome subunit alpha type-1 Protein. | |
| The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome . Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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