PDF DatasheetHuman Regulator of G-protein signaling 20 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Regulator of G-protein signaling 20 based upon sequence from Human
Host: QP6604 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Regulator of G-protein signaling 20, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6604.
Bioactivity Data: Untested
Full Length? Full Length of BC015614
Amino Acid Sequence: EPAGASSPAG RVDGGLQMGS ERMEMRKRQM PAAQDTPGAA PGQPGAGSRG SNACCFCWCC CCSCSCLTVR NQEDQRPTIA SHELRADLPT WEESPAPTLE EVNAWAQSFD KLMVTPAGRN AFREFLRTEF SEENMLFWMA CEELKKEANK NIIEEKARII YEDYISILSP KEVSLDSRVR EVINRNMVEP SQHIFDDAQL QIYTLMHRDS YPRFMNSAVY KDLLQSLSEK SIEA
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Regulator of G-protein signaling 20 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Regulator of G-protein signaling 20 Protein General Information | |
|---|---|
| Alternate Names | |
| ZGAP1, g(z)GAP, RGSZ1, gz-GAP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RGS20 |
| Entrez Gene ID | 8601 |
| Ensemble Gene ID | ENSG00000147509 |
| RefSeq Protein Accession(s) | NP_001273602.1 |
| RefSeq mRNA Accession(s) | NM_001286673.1, NM_001286674.1, NM_001286675.1, NM_003702.4, NM_170587.3, XM_011517622.2 |
| UniProt ID(s) | O76081 |
| UniGene ID(s) | Hs.368733 |
| HGNC ID(s) | HGNC:14600 |
| COSMIC ID Link(s) | RGS20 |
| KEGG Gene ID(s) | hsa:8601 |
| PharmGKB ID(s) | PA34373 |
| General Description of Recombinant Human Regulator of G-protein signaling 20 Protein. | |
| Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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