PDF DatasheetE. coli 8-oxo-dGTP diphosphatase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant 8-oxo-dGTP diphosphatase based upon sequence from: E. coli
Host: QP7301 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Escherichia coli (strain K12) 8-oxo-dGTP diphosphatase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7301.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu129
Amino Acid Sequence: MKKLQIAVGI IRNENNEIFI TRRAADAHMA NKLEFPGGKI EMGETPEQAV VRELQEEVGI TPQHFSLFEK LEYEFPDRHI TLWFWLVERW EGEPWGKEGQ PGEWMSLVGL NADDFPPANE PVIAKLKRL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of E. coli 8-oxo-dGTP diphosphatase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant E. coli 8-oxo-dGTP diphosphatase Protein General Information | |
|---|---|
| Alternate Names | |
| nudA; b0099; ECK0100; JW0097 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | mutT |
| Entrez Gene ID | 944824 |
| RefSeq Protein Accession(s) | NP_414641.1 |
| RefSeq mRNA Accession(s) | NC_000913.3, NZ_LN832404.1 |
| UniProt ID(s) | P08337 |
| KEGG Gene ID(s) | ecj:JW0097 |
| General Description of Recombinant E. coli 8-oxo-dGTP diphosphatase Protein. | |
| Involved in the GO syst responsible for roving an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of tplate DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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