PDF DatasheetHuman IL1F10 / IL-38 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL1F10 / IL-38 based upon sequence from: Human
Host: QP7890 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL1F10 / IL-38, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7890.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Trp152
Amino Acid Sequence: MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICILPNRGL ARTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL1F10 / IL-38 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL1F10 / IL-38 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Il1f10 |
| Entrez Gene ID | 84639 |
| Ensemble Gene ID | ENSG00000136697 |
| RefSeq Protein Accession(s) | NP_115945.4 |
| RefSeq mRNA Accession(s) | NM_032556.5, NM_173161.2 |
| UniProt ID(s) | Q8WWZ1 |
| UniGene ID(s) | Hs.306974 |
| HGNC ID(s) | HGNC:15552 |
| COSMIC ID Link(s) | Il1f10 |
| KEGG Gene ID(s) | hsa:84639 |
| PharmGKB ID(s) | PA38387 |
| General Description of Recombinant Human IL1F10 / IL-38 Protein. | |
| Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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