PDF DatasheetHuman KLRG1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant KLRG1 based upon sequence from: Human
Host: QP7938 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) KLRG1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7938.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Leu60 – Phe195
Amino Acid Sequence: LCQGSNYSTC ASCPSCPDRW MKYGNHCYYF SVEEKDWNSS LEFCLARDSH LLVITDNQEM SLLQVFLSEA FCWIGLRNNS GWRWEDGSPL NFSRISSNSF VQTCGAINKN GLQASSCEVP LHWVCKKCPF ADQALF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human KLRG1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human KLRG1 Protein General Information | |
|---|---|
| Alternate Names | |
| MAFA-LIKE; MAFA-2F1; MAFA-L; 2F1; CLEC15A; MAFA; Killer cell lectin-like receptor subfamily G member | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KLRG1 |
| Entrez Gene ID | 10219 |
| Ensemble Gene ID | ENSG00000139187 |
| RefSeq Protein Accession(s) | NP_001316028.1 |
| RefSeq mRNA Accession(s) | NM_001329099.1, NM_005810.3 |
| UniProt ID(s) | Q96E93 |
| UniGene ID(s) | Hs.558446 |
| HGNC ID(s) | HGNC:6380 |
| COSMIC ID Link(s) | KLRG1 |
| KEGG Gene ID(s) | hsa:10219 |
| PharmGKB ID(s) | PA30170 |
| General Description of Recombinant Human KLRG1 Protein. | |
| Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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