PDF DatasheetHuman Intraflagellar transport protein 27 homolog Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Intraflagellar transport protein 27 homolog based upon sequence from: Human
Host: QP8131 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Intraflagellar transport protein 27 homolog, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8131.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ala186
Amino Acid Sequence: MVKLAAKCIL AGDPAVGKTA LAQIFRSDGA HFQKSYTLTT GMDLVVKTVP VPDTGDSVEL FIFDSAGKEL FSEMLDKLWE SPNVLCLVYD VTNEESFNNC SKWLEKARSQ APGISLPGVL VGNKTDLAGR RAVDSAEARA WALGQGLECF ETSVKEMENF EAPFHCLAKQ FHQLYREKVE VFRALA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Intraflagellar transport protein 27 homolog Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Intraflagellar transport protein 27 homolog Protein General Information | |
|---|---|
| Alternate Names | |
| RABL4; BBS19; RAYL | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IFT27 |
| Entrez Gene ID | 11020 |
| Ensemble Gene ID | ENSG00000100360 |
| RefSeq Protein Accession(s) | NP_001171172.1 |
| RefSeq mRNA Accession(s) | NM_001177701.2, NM_006860.4, XM_006724106.2 |
| UniProt ID(s) | Q9BW83 |
| UniGene ID(s) | Hs.415172 |
| HGNC ID(s) | HGNC:18626 |
| COSMIC ID Link(s) | IFT27 |
| KEGG Gene ID(s) | hsa:11020 |
| PharmGKB ID(s) | PA38609 |
| General Description of Recombinant Human Intraflagellar transport protein 27 homolog Protein. | |
| Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 . Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 . Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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