PDF DatasheetHuman Origin recognition complex subunit 6 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Origin recognition complex subunit 6 based upon sequence from: Human
Host: QP8259 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Origin recognition complex subunit 6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8259.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Glu252
Amino Acid Sequence: MGSELIGRLA PRLGLAEPDM LRKAEEYLRL SRVKCVGLSA RTTETSSAVM CLDLAASWMK CPLDRAYLIK LSGLNKETYQ SCLKSFECLL GLNSNIGIRD LAVQFSCIEA VNMASKILKS YESSLPQTQQ VDLDLSRPLF TSAALLSACK ILKLKVDKNK MVATSGVKKA IFDRLCKQLE KIGQQVDREP GDVATPPRKR KKIVVEAPAK EMEKVEEMPH KPQKDEDLTQ DYEEWKRKIL ENAASAQKAT AE
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Origin recognition complex subunit 6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Origin recognition complex subunit 6 Protein General Information | |
|---|---|
| Alternate Names | |
| ORC6L | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ORC6 |
| Entrez Gene ID | 23594 |
| Ensemble Gene ID | ENSG00000091651 |
| RefSeq Protein Accession(s) | NP_055136.1 |
| RefSeq mRNA Accession(s) | NM_014321.3 |
| UniProt ID(s) | Q9Y5N6 |
| UniGene ID(s) | Hs.49760 |
| HGNC ID(s) | HGNC:17151 |
| COSMIC ID Link(s) | ORC6 |
| KEGG Gene ID(s) | hsa:23594 |
| PharmGKB ID(s) | PA32813 |
| General Description of Recombinant Human Origin recognition complex subunit 6 Protein. | |
| Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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