PDF DatasheetHuman Proteasome subunit beta type-4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Proteasome subunit beta type-4 based upon sequence from: Human
Host: QP8363 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Proteasome subunit beta type-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8363.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Thr46 – Glu264
Amino Acid Sequence: TQNPMVTGTS VLGVKFEGGV VIAADMLGSY GSLARFRNIS RIMRVNNSTM LGASGDYADF QYLKQVLGQM VIDEELLGDG HSYSPRAIHS WLTRAMYSRR SKMNPLWNTM VIGGYADGES FLGYVDMLGV AYEAPSLATG YGAYLAQPLL REVLEKQPVL SQTEARDLVE RCMRVLYYRD ARSYNRFQIA TVTEKGVEIE GPLSTETNWD IAHMISGFE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Proteasome subunit beta type-4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Proteasome subunit beta type-4 Protein General Information | |
|---|---|
| Alternate Names | |
| HsN3; HN3; PROS-26; PROS26 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PSMB4 |
| Entrez Gene ID | 5692 |
| Ensemble Gene ID | ENSG00000159377 |
| RefSeq Protein Accession(s) | NP_002787.2 |
| RefSeq mRNA Accession(s) | NM_002796.2 |
| UniProt ID(s) | P28070 |
| UniGene ID(s) | Hs.89545 |
| HGNC ID(s) | HGNC:9541 |
| COSMIC ID Link(s) | PSMB4 |
| KEGG Gene ID(s) | hsa:5692 |
| PharmGKB ID(s) | PA33886 |
| General Description of Recombinant Human Proteasome subunit beta type-4 Protein. | |
| The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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