PDF DatasheetHuman MPRI Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MPRI based upon sequence from: Human
Host: QP8603 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MPRI, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8603.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys2328 – Ile2491
Amino Acid Sequence: KKERRETVIS KLTTCCRRSS NVSYKYSKVN KEEETDENET EWLMEEIQLP PPRQGKEGQE NGHITTKSVK ALSSLHGDDQ DSEDEVLTIP EVKVHSGRGA GAESSHPVRN AQSNALQERE DDRVGLVRGE KARKGKSSSA QQKTVSSTKL VSFHDDSDED LLHI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MPRI Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MPRI Protein General Information | |
|---|---|
| Alternate Names | |
| MPR1; CIMPR; M6P/IGF2R; M6P-R; CD222; CI-M6PR; MPR300; MPR 300; MPRI; Cation-independent mannose-6-phosphate recept | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MPRI |
| Entrez Gene ID | 3482 |
| Ensemble Gene ID | ENSG00000197081 |
| RefSeq Protein Accession(s) | NP_000867.2 |
| RefSeq mRNA Accession(s) | NM_000876.3 |
| UniProt ID(s) | P11717 |
| UniGene ID(s) | Hs.487062 |
| HGNC ID(s) | HGNC:5467 |
| KEGG Gene ID(s) | hsa:3482 |
| PharmGKB ID(s) | PA29701 |
| General Description of Recombinant Human MPRI Protein. | |
| Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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