PDF DatasheetHuman C-X-C chemokine receptor type 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C-X-C chemokine receptor type 3 based upon sequence from: Human
Host: QP9091 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) C-X-C chemokine receptor type 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9091.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu368
Amino Acid Sequence: MVLEVSDHQV LNDAEVAALL ENFSSSYDYG ENESDSCCTS PPCPQDFSLN FDRAFLPALY SLLFLLGLLG NGAVAAVLLS RRTALSSTDT FLLHLAVADT LLVLTLPLWA VDAAVQWVFG SGLCKVAGAL FNINFYAGAL LLACISFDRY LNIVHATQLY RRGPPARVTL TCLAVWGLCL LFALPDFIFL SAHHDERLNA THCQYNFPQV GRTALRVLQL VAGFLLPLLV MAYCYAHILA VLLVSRGQRR LRAMRLVVVV VVAFALCWTP YHLVVLVDIL MDLGALARNC GRESRVDVAK SVTSGLGYMH CCLNPLLYAF VGVKFRERMW MLLLRLGCPN QRGLQRQPSS SRRDSSWSET SEASYSGL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human C-X-C chemokine receptor type 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-X-C chemokine receptor type 3 Protein General Information | |
|---|---|
| Alternate Names | |
| GPR9; CD182; CKR-L2; MigR; CD183; CMKAR3; IP10-R; Mig-R | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCR3 |
| Entrez Gene ID | 2833 |
| Ensemble Gene ID | ENSG00000186810 |
| RefSeq Protein Accession(s) | NP_001136269.1 |
| RefSeq mRNA Accession(s) | NM_001142797.1, NM_001504.1, XM_017029435.1 |
| UniProt ID(s) | P49682 |
| UniGene ID(s) | Hs.198252 |
| HGNC ID(s) | HGNC:4540 |
| COSMIC ID Link(s) | CXCR3 |
| KEGG Gene ID(s) | hsa:2833 |
| PharmGKB ID(s) | PA35049 |
| General Description of Recombinant Human C-X-C chemokine receptor type 3 Protein. | |
| Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway . Binds to CCL21. Probably promotes cell chemotaxis response. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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