PDF DatasheetHuman Interleukin-26 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Interleukin-26 based upon sequence from Human
Host: QP9904 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Interleukin-26, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9904.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Lys22 – Gln171
Amino Acid Sequence: KHKQSSFTKS CYPRGTLSQA VDALYIKAAW LKATIPEDRI KNIRLLKKKT KKQFMKNCQF QEQLLSFFME DVFGQLQLQG CKKIRFVEDF HSLRQKLSHC ISCASSAREM KSITRMKRIF YRIGNKGIYK AISELDILLS WIKKLLESSQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Interleukin-26 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Interleukin-26 Protein General Information | |
|---|---|
| Alternate Names | |
| IL-26; AK155 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL26 |
| Entrez Gene ID | 55801 |
| Ensemble Gene ID | ENSG00000111536 |
| RefSeq Protein Accession(s) | NP_060872.1 |
| RefSeq mRNA Accession(s) | NM_018402.1 |
| UniProt ID(s) | Q9NPH9 |
| UniGene ID(s) | Hs.272350 |
| HGNC ID(s) | HGNC:17119 |
| COSMIC ID Link(s) | IL26 |
| KEGG Gene ID(s) | hsa:55801 |
| PharmGKB ID(s) | PA29826 |
| General Description of Recombinant Human Interleukin-26 Protein. | |
| May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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