PDF DatasheetRat and Mouse Anti-Epcam / CD326 Antibody Product Attributes
Species: Rat and Mouse. Does not cross-react with Human Epcam.
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Epcam / CD326 Antibody Clone: Epcam/1159
Clone Epcam/1159 Host and Isotype: Mouse IgG1
Anti-Rat, Mouse, and Human (-) Epcam / CD326 Positive Control Sample: Recombinant full-length rat Epcam protein
Cellular Localization of Antibody Cell surface
Buffer and Stabilizer: Bioreactor Concentrate with 0.05% Azide.
Antibody Concentration: Not applicable
Antibody Purification Method:Bioreactor Concentrate
Immunogen: Recombinant full-length Rat Epcam protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Epcam / CD326 Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-EPCAM antibody staining is expected to be primarily localized to the plasma membrane.
Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of Epcam / CD326 expression as measured by anti-Epcam / CD326 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.
| Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal Intensity | – | + | + | +++ | +++ | – | – | – | +++ | – | – | +++ | – | +++ | – | – | – | – | +++ | – |
| EPCAM Variability | ++ | +++ | +++ | + | + | + | ++ | + | ++ | + | + | ++ | + | + | + | ++ | ++ | ++ | + | + |
| Epcam / CD326 General Information | |
|---|---|
| Alternate Names | |
| EpCAM, Epithelial cell adhesion molecule, EGP40, CD326, Cluster of Differentiation 326 | |
| Molecular Weight | |
| 40-43kDa | |
| Chromosomal Location | |
| 6q12 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Epcam |
| Entrez Gene ID | 171577 |
| Ensemble Gene ID | ENSRNOG00000015667 |
| RefSeq Protein Accession(s) | XP_017449516, NP_612550 |
| RefSeq mRNA Accession(s) | XM_017594027, NM_138541 |
| RefSeq Genomic Accession(s) | NC_005105, AC_000074 |
| UniProt ID(s) | O55159 |
| UniGene ID(s) | O55159 |
| Cosmic ID(s) | Epcam |
| KEGG Gene ID(s) | rno:171577 |
| General Description of Epcam / CD326. | |
| Epitopes of Epcam/1158, Epcam/1159 monoclonal antibodies are different. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Epcam). It is expressed on baso-lateral cell surface in most simple epithelia, a vast majority of carcinomas. | |
Limitations and Warranty
enQuire Bio’s Epcam / CD326 Anti-Rat, Mouse Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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