Human, Horse, and Rat (-) Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Product Attributes
Species: Human, Horse, and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Clone: NKI-beteb
Clone NKI-beteb Host and Isotype: Mouse IgG2b kappa
Anti-Human, Horse, and Rat (-) gp100 / Melanosome / PMEL17 / SILV Positive Control Sample: SK-MEL-28 cells or Melanoma
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Membranes from a human melanoma metastasis
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
gp100 / Melanosome / PMEL17 / SILV Previously Observed Antibody Staining Patterns
gp100 / Melanosome / PMEL17 / SILV General Information | |
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Alternate Names | |
Melanocyte protein PMEL, Premelanosome protein, PMEL, Silver locus protein homolog, SILV | |
Molecular Weight | |
90-100kDa | |
Chromosomal Location | |
12q13.2 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | SILV |
Entrez Gene ID | 6490 |
Ensemble Gene ID | ENSG00000185664 |
RefSeq Protein Accession(s) | NP_001186982, XP_006719632, NP_001307050, NP_008859, XP_011536987, NP_001186983, NP_001307051 |
RefSeq mRNA Accession(s) | XM_006719569, NM_001320122, NM_001200053, XM_011538685, NM_001320121, NM_006928 NM_001200054 |
RefSeq Genomic Accession(s) | NC_000012, NC_018923, NG_028086 |
UniProt ID(s) | P40967 |
UniGene ID(s) | P40967 |
HGNC ID(s) | 10880 |
Cosmic ID(s) | PMEL |
KEGG Gene ID(s) | hsa:6490 |
PharmGKB ID(s) | PA35781 |
General Description of gp100 / Melanosome / PMEL17 / SILV. | |
By immunohistochemistry, it specifically recognizes a protein in melanocytes, melanomas. This MAb reacts with junctional, blue nevus cells, variably with fetal, neonatal melanocytes. Intradermal nevi, normal adult melanocytes,, non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas, other tumors showing melanocytic differentiation. |
Limitations and Warranty
enQuire Bio’s gp100 / Melanosome / PMEL17 / SILV Anti-Human, Horse Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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