Anti-GRP94 / HSP90B1 Antibody Clone SPM249

Observed Antibody Staining Data By Tissue Type:

Variations in GRP94 / HSP90B1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in the endometrial stroma in endometrium, cells in the molecular layer in cerebellum, cells in the seminiferous ducts in testis, cells in the tubules in kidney, decidual cells in the placenta, endothelial cells in the colon, exocrine glandular cells in the pancreas, fibroblasts in skin, follicle cells in the ovary, germinal center cells in the tonsil, glandular cells in the adrenal gland, appendix, breast, cervix, uterine, colon, duodenum, endometrium, epididymis, fallopian tube, gallbladder, parathyroid gland, prostate, rectum, seminal vesicle, small intestine, stomach and thyroid gland, glial cells in the caudate nucleus, cerebral cortex and hippocampus, hematopoietic cells in the bone marrow, islets of Langerhans in pancreas, macrophages in lung, neuronal cells in the caudate nucleus, cerebral cortex and hippocampus, ovarian stroma cells in the ovary, Purkinje cells in the cerebellum, respiratory epithelial cells in the bronchus and nasopharynx, trophoblastic cells in the placenta and urothelial cells in the urinary bladder. More moderate antibody staining intensity was present in cells in the endometrial stroma in endometrium, cells in the molecular layer in cerebellum, cells in the seminiferous ducts in testis, cells in the tubules in kidney, decidual cells in the placenta, endothelial cells in the colon, exocrine glandular cells in the pancreas, fibroblasts in skin, follicle cells in the ovary, germinal center cells in the tonsil, glandular cells in the adrenal gland, appendix, breast, cervix, uterine, colon, duodenum, endometrium, epididymis, fallopian tube, gallbladder, parathyroid gland, prostate, rectum, seminal vesicle, small intestine, stomach and thyroid gland, glial cells in the caudate nucleus, cerebral cortex and hippocampus, hematopoietic cells in the bone marrow, islets of Langerhans in pancreas, macrophages in lung, neuronal cells in the caudate nucleus, cerebral cortex and hippocampus, ovarian stroma cells in the ovary, Purkinje cells in the cerebellum, respiratory epithelial cells in the bronchus and nasopharynx, trophoblastic cells in the placenta and urothelial cells in the urinary bladder. Low, but measureable presence of GRP94 / HSP90B1 could be seen inmyocytes in skeletal muscle and peripheral nerve in mesenchymal tissue. We were unable to detect GRP94 / HSP90B1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.