Human GRP94 / HSP90B1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GRP94 / HSP90B1 based upon sequence from: Human
Host: QP8707 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GRP94 / HSP90B1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8707.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val27 – Glu799
Amino Acid Sequence: VDGTVEEDLG KSREGSRTDD EVVQREEEAI QLDGLNASQI RELREKSEKF AFQAEVNRMM KLIINSLYKN KEIFLRELIS NASDALDKIR LISLTDENAL SGNEELTVKI KCDKEKNLLH VTDTGVGMTR EELVKNLGTI AKSGTSEFLN KMTEAQEDGQ STSELIGQFG VGFYSAFLVA DKVIVTSKHN NDTQHIWESD SNEFSVIADP RGNTLGRGTT ITLVLKEEAS DYLELDTIKN LVKKYSQFIN FPIYVWSSKT ETVEEPMEEE EAAKEEKEES DDEAAVEEEE EEKKPKTKKV EKTVWDWELM NDIKPIWQRP SKEVEEDEYK AFYKSFSKES DDPMAYIHFT AEGEVTFKSI LFVPTSAPRG LFDEYGSKKS DYIKLYVRRV FITDDFHDMM PKYLNFVKGV VDSDDLPLNV SRETLQQHKL LKVIRKKLVR KTLDMIKKIA DDKYNDTFWK EFGTNIKLGV IEDHSNRTRL AKLLRFQSSH HPTDITSLDQ YVERMKEKQD KIYFMAGSSR KEAESSPFVE RLLKKGYEVI YLTEPVDEYC IQALPEFDGK RFQNVAKEGV KFDESEKTKE SREAVEKEFE PLLNWMKDKA LKDKIEKAVV SQRLTESPCA LVASQYGWSG NMERIMKAQA YQTGKDISTN YYASQKKTFE INPRHPLIRD MLRRIKEDED DKTVLDLAVV LFETATLRSG YLLPDTKAYG DRIERMLRLS LNIDPDAKVE EEPEEEPEET AEDTTEDTEQ DEDEEMDVGT DEEEETAKES TAE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GRP94 / HSP90B1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human GRP94 / HSP90B1 Protein General Information | |
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Alternate Names | |
GRP94; HSP90B1; ECGP; HEL35; TRA1; HEL-S-125m; GP96; GRP94 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | HSP90B1 |
Entrez Gene ID | 7184 |
Ensemble Gene ID | ENSG00000166598 |
RefSeq Protein Accession(s) | NP_003290.1 |
RefSeq mRNA Accession(s) | NM_003299.2 |
UniProt ID(s) | P14625 |
UniGene ID(s) | Hs.192374 |
HGNC ID(s) | HGNC:12028 |
COSMIC ID Link(s) | HSP90B1 |
KEGG Gene ID(s) | hsa:7184 |
PharmGKB ID(s) | PA36705 |
General Description of Recombinant Human GRP94 / HSP90B1 Protein. | |
Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors . Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.1 Publication |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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