Formalin-fixed, paraffin embedded human tonsil sections stained with 100 ul anti-Lambda Light Chain (clone ICO-106) at 1:50. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

Formalin-fixed, paraffin-embedded human Tonsil stained with Lambda Light Chain Monoclonal Antibody (ICO-16).

Anti-Lambda Light Chain Antibody Clone ICO-106

Name: Anti-Lambda Light Chain Antibody Clone ICO-106
SKU: 3535-MSM1-P1
Price: 429.00 USD
Availability: InStock

$ 429.00

SKU: 3535-MSM1
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Size

Tag

Clear

SKU: 3535-MSM1-P1 Categories: Antibody, Flow Cytometry, Human, IgG1 kappa, Immunofluorescence, Immunohistochemistry (IHC), Mouse, Not MS Validated, Unconjugated Tag: Lambda Light Chain

PDF Datasheet

Human Anti-Lambda Light Chain Antibody Product Attributes

Species: Human

Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).

Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)

Clonality: Monoclonal

Anti-Lambda Light Chain Antibody Clone: ICO-106

Clone ICO-106 Host and Isotype: Mouse IgG1 kappa

Anti-Human Lambda Light Chain Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen

Cellular Localization of Antibody Cell surface, cytoplasmic, secreted

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Purified human IgG

Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Lambda Light Chain Previously Observed Antibody Staining Patterns

Lambda Light Chain General Information

Alternate Names

IGL, Indole-3-glycerol-phosphate lyase

Molecular Weight

~22.5kDa

Chromosomal Location

22q11.22

Curated Database and Bioinformatic Data

Gene Symbol IGL

Entrez Gene ID 3535, 3546

RefSeq Genomic Accession(s) NC_000022, NC_018933, NG_000002

UniGene ID(s)

HGNC ID(s) 5853

Cosmic ID(s) IGL, IGLV@

General Description of Lambda Light Chain.

This MAb is specific to lambda light chain of immunoglobulin, shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas,, certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Limitations and Warranty

enQuire Bio’s Lambda Light Chain Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

Size
100 ug

Tag
Unconjugated

Buffer and Stabilizer
10mM PBS with 0.05% BSA & 0.05% azide., 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.

Product Type
Antibody

Host
Mouse

Isotype
IgG1, kappa

Applications
ICC/IF

Species
Human

Mass Spec Validated?
Not MS Validated

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Lambda Light Chain General Information
Alternate Names
IGL, Indole-3-glycerol-phosphate lyase
Molecular Weight
~22.5kDa
Chromosomal Location
22q11.22
Curated Database and Bioinformatic Data
Gene Symbol	IGL
Entrez Gene ID	3535, 3546
RefSeq Genomic Accession(s)	NC_000022, NC_018933, NG_000002
UniGene ID(s)
HGNC ID(s)	5853
Cosmic ID(s)	IGL, IGLV@
General Description of Lambda Light Chain.
This MAb is specific to lambda light chain of immunoglobulin, shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas,, certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Size	100 ug
Tag	Unconjugated
Buffer and Stabilizer	10mM PBS with 0.05% BSA & 0.05% azide., 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Product Type	Antibody
Host	Mouse
Isotype	IgG1, kappa
Applications	ICC/IF
Species	Human
Mass Spec Validated?	Not MS Validated