Formalin-fixed, paraffin-embedded human Tonsil stained with Lambda Light Chain Monoclonal Antibody (N1/2).

Anti-Lambda Light Chain Antibody Clone N10/2

Name: Anti-Lambda Light Chain Antibody Clone N10/2
SKU: 3535-MSM7-P0
Availability: InStock

$ 228.00 – $ 518.00

SKU: 3535-MSM7
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Size

Tag

Clear

SKU: 3535-MSM7-P0 Categories: Antibody, Human, IgG1 kappa, Immunohistochemistry (IHC), Mouse, Not MS Validated, Unconjugated Tag: Lambda Light Chain

PDF Datasheet

Human Anti-Lambda Light Chain Antibody Product Attributes

Species: Human

Tested Applications: Immunohistochemistry (IHC).

Clonality: Monoclonal

Anti-Lambda Light Chain Antibody Clone: N10/2

Clone N10/2 Host and Isotype: Mouse IgG1 kappa

Anti-Human Lambda Light Chain Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen

Cellular Localization of Antibody Cell Surface, cytoplasmic and secreted

Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide

Antibody Concentration: 200 ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Purified IgG from human serum

Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Lambda Light Chain Previously Observed Antibody Staining Patterns

Lambda Light Chain General Information

Alternate Names

IGL, Indole-3-glycerol-phosphate lyase

Molecular Weight

22.5kDa

Chromosomal Location

22q11.22

Curated Database and Bioinformatic Data

Gene Symbol IGL

Entrez Gene ID 3535, 3546

RefSeq Genomic Accession(s) NC_000022, NC_018933, NG_000002

UniGene ID(s)

HGNC ID(s) 5853

Cosmic ID(s) IGL, IGLV@

General Description of Lambda Light Chain.

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Limitations and Warranty

enQuire Bio’s Lambda Light Chain Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

Size
20 ug, 100 ug, 200 ug

Tag
Unconjugated

Buffer and Stabilizer
10mM PBS with 0.05% BSA and 0.05% Azide

Product Type
Antibody

Host
Mouse

Isotype
IgG1, kappa

Applications
IHC

Species
Human

Mass Spec Validated?
Not MS Validated

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Lambda Light Chain General Information
Alternate Names
IGL, Indole-3-glycerol-phosphate lyase
Molecular Weight
22.5kDa
Chromosomal Location
22q11.22
Curated Database and Bioinformatic Data
Gene Symbol	IGL
Entrez Gene ID	3535, 3546
RefSeq Genomic Accession(s)	NC_000022, NC_018933, NG_000002
UniGene ID(s)
HGNC ID(s)	5853
Cosmic ID(s)	IGL, IGLV@
General Description of Lambda Light Chain.
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Size	20 ug, 100 ug, 200 ug
Tag	Unconjugated
Buffer and Stabilizer	10mM PBS with 0.05% BSA and 0.05% Azide
Product Type	Antibody
Host	Mouse
Isotype	IgG1, kappa
Applications	IHC
Species	Human
Mass Spec Validated?	Not MS Validated