.jpg "S100A1 IHC human Melanoma (4C4.9)")
PDF DatasheetHuman, Mouse, Rat, Cow Anti-S100A1 Antibody Product Attributes
Species: Human, Mouse, Rat, and Cow
Cross Reactivity:
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-S100A1 Antibody Clone: 4C4.9
Clone 4C4.9 Host and Isotype: Mouse IgG2a, kappa
Anti-Human ;Mouse ;Rat ;Cow S100A1 Positive Control Sample: Brain, Melanoma
Cellular Localization of Antibody <4C4.9 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified bovine brain S100 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
S100A1 Previously Observed Antibody Staining Patterns
| S100A1 General Information | |
|---|---|
| Alternate Names | |
| Molecular Weight | |
| 10-12kDa | |
| Chromosomal Location | |
| 1q21.3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | S100A1 |
| Entrez Gene ID | 6271 |
| UniProt ID(s) | P23297 |
| General Description of S100A1. | |
| S100 belongs to the family of calcium binding proteins. S100A, S100B proteins are two members of the S100 family. S100A is composed of an alpha, beta chain whereas S100B is composed of two beta chains. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal, cardiac muscle, Schwann cells, epithelial, myoepithelial cells of the breast, salivary, sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose, cartilaginous tissue,, Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas, cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas, their metastases. | |
Limitations and Warranty
This product is for Research Use Only. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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