PDF DatasheetHuman Anti-S100B Antibody Product Attributes
Species: Human
Cross Reactivity:
Tested Applications: Immunohistochemistry (IHC).
Clonality: Recombinant Monoclonal
Anti-S100A1 Antibody Clone: S100B/1706R
Clone S100A1/1706R Host and Isotype: Rabbit IgG, kappa
Anti-Human S100A1 Positive Control Sample: Brain, Melanoma
Cellular Localization of Antibody <S100B/1706R Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with or without 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant full-length human S100B protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
S100B Previously Observed Antibody Staining Patterns
| S100A1 General Information | |
|---|---|
| Alternate Names | |
| Molecular Weight | |
| 10-12kDa | |
| Chromosomal Location | |
| 21q22.3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | S100B |
| Entrez Gene ID | 6285 |
| UniProt ID(s) | P04271 |
| General Description of S100B. | |
| S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. | |
Limitations and Warranty
This product is for Research Use Only. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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